Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:enteropeptidase
|
| gptkbp:CASNumber |
9014-74-8
|
| gptkbp:catalyzes |
cleaves Lys-Ile bond in trypsinogen
|
| gptkbp:cofactor |
none
|
| gptkbp:discoveredBy |
gptkb:Wilhelm_Kühne
|
| gptkbp:discoveredIn |
1876
|
| gptkbp:EC_number |
3.4.21.9
|
| gptkbp:foundIn |
gptkb:duodenum
|
| gptkbp:function |
activates trypsinogen to trypsin
|
| gptkbp:gene |
TMPRSS15
|
| gptkbp:locale |
brush border of small intestine
|
| gptkbp:molecularWeight |
~150 kDa
|
| gptkbp:producedBy |
intestinal mucosa
|
| gptkbp:significance |
deficiency causes protein malabsorption
|
| gptkbp:species |
humans
other vertebrates |
| gptkbp:structure |
gptkb:serine_protease
|
| gptkbp:substrate |
trypsinogen
|
| gptkbp:UniProtID |
Q90059 (human)
|
| gptkbp:bfsParent |
gptkb:Protease,_serine,_1_(trypsin_1)
gptkb:serine_protease_1 gptkb:enteropeptidase |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
enterokinase
|