Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alsoKnownAs |
gptkb:enteropeptidase
|
gptkbp:CASNumber |
9014-74-8
|
gptkbp:catalyzes |
cleaves Lys-Ile bond in trypsinogen
|
gptkbp:cofactor |
none
|
gptkbp:discoveredBy |
gptkb:Wilhelm_Kühne
|
gptkbp:discoveredIn |
1876
|
gptkbp:EC_number |
3.4.21.9
|
gptkbp:foundIn |
gptkb:duodenum
|
gptkbp:function |
activates trypsinogen to trypsin
|
gptkbp:gene |
TMPRSS15
|
https://www.w3.org/2000/01/rdf-schema#label |
enterokinase
|
gptkbp:locale |
brush border of small intestine
|
gptkbp:molecularWeight |
~150 kDa
|
gptkbp:producedBy |
intestinal mucosa
|
gptkbp:significance |
deficiency causes protein malabsorption
|
gptkbp:species |
humans
other vertebrates |
gptkbp:structure |
gptkb:serine_protease
|
gptkbp:substrate |
trypsinogen
|
gptkbp:UniProtID |
Q90059 (human)
|
gptkbp:bfsParent |
gptkb:serine_protease_1
gptkb:enteropeptidase |
gptkbp:bfsLayer |
7
|