Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
gptkb:endoglin
|
gptkbp:associatedWith |
gptkb:hereditary_hemorrhagic_telangiectasia
angiogenesis |
gptkbp:discoveredIn |
1980s
|
gptkbp:expressedIn |
gptkb:placenta
vascular endothelial cells some tumor cells activated monocytes |
gptkbp:function |
TGF-beta receptor complex component
|
gptkbp:gene |
gptkb:ENG
|
https://www.w3.org/2000/01/rdf-schema#label |
CD105
|
gptkbp:involvedIn |
cell proliferation
cell migration vascular development |
gptkbp:locatedOnChromosome |
gptkb:chromosome_9
|
gptkbp:marking |
mesenchymal stem cells
|
gptkbp:molecularWeight |
~180 kDa
|
gptkbp:structure |
homodimeric membrane glycoprotein
|
gptkbp:target |
TRC105 (therapeutic antibody)
|
gptkbp:UniProtID |
P17813
|
gptkbp:bfsParent |
gptkb:ENG_gene
|
gptkbp:bfsLayer |
7
|