CD105

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:endoglin
gptkbp:associatedWith gptkb:hereditary_hemorrhagic_telangiectasia
angiogenesis
gptkbp:discoveredIn 1980s
gptkbp:expressedIn gptkb:placenta
vascular endothelial cells
some tumor cells
activated monocytes
gptkbp:function TGF-beta receptor complex component
gptkbp:gene gptkb:ENG
https://www.w3.org/2000/01/rdf-schema#label CD105
gptkbp:involvedIn cell proliferation
cell migration
vascular development
gptkbp:locatedOnChromosome gptkb:chromosome_9
gptkbp:marking mesenchymal stem cells
gptkbp:molecularWeight ~180 kDa
gptkbp:structure homodimeric membrane glycoprotein
gptkbp:target TRC105 (therapeutic antibody)
gptkbp:UniProtID P17813
gptkbp:bfsParent gptkb:ENG_gene
gptkbp:bfsLayer 7