Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
alkaloid
anti-protozoal drug |
| gptkbp:ATCCode |
P01CX01
|
| gptkbp:CASNumber |
483-18-1
|
| gptkbp:category |
antineoplastic agent
isoquinoline alkaloid emetic |
| gptkbp:chemicalFormula |
C29H40N2O4
|
| gptkbp:discoveredBy |
gptkb:Pierre-Joseph_Pelletier
gptkb:Joseph_Bienaimé_Caventou |
| gptkbp:discoveredIn |
1817
|
| gptkbp:foundIn |
ipecac root
|
| https://www.w3.org/2000/01/rdf-schema#label |
emetine
|
| gptkbp:IUPACName |
(R)-2-[(2S,3R,11bS)-3-ethyl-1,2,3,4,6,7,11,11b-octahydro-1,3-dimethoxy-6,11b-dimethyl-5H-benzo[a]quinolizin-2-yl]isoquinolin-6-ol
|
| gptkbp:mechanismOfAction |
inhibits protein synthesis
|
| gptkbp:meltingPoint |
102-106°C
|
| gptkbp:molecularWeight |
480.64 g/mol
|
| gptkbp:origin |
Cephaelis ipecacuanha
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL1200692
10221 9802 |
| gptkbp:routeOfAdministration |
oral
intramuscular |
| gptkbp:sideEffect |
nausea
vomiting cardiotoxicity |
| gptkbp:solubility |
slightly soluble in water
soluble in alcohol |
| gptkbp:toxicity |
cardiotoxic
|
| gptkbp:UNII |
6T8X9E0653
|
| gptkbp:usedFor |
treatment of amoebiasis
|
| gptkbp:bfsParent |
gptkb:isoquinoline_alkaloids
|
| gptkbp:bfsLayer |
7
|