emetine

URI: https://gptkb.org/entity/emetine
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:alkaloid
gptkb:anti-protozoal_drug
gptkbp:ATCCode P01CX01
gptkbp:CASNumber 483-18-1
gptkbp:category gptkb:emetic
gptkb:antineoplastic_agent
gptkb:isoquinoline_alkaloid
gptkbp:chemicalFormula C29H40N2O4
gptkbp:discoveredBy gptkb:Pierre-Joseph_Pelletier
gptkb:Joseph_Bienaimé_Caventou
gptkbp:discoveredIn 1817
gptkbp:foundIn ipecac root
gptkbp:IUPACName (R)-2-[(2S,3R,11bS)-3-ethyl-1,2,3,4,6,7,11,11b-octahydro-1,3-dimethoxy-6,11b-dimethyl-5H-benzo[a]quinolizin-2-yl]isoquinolin-6-ol
gptkbp:mechanismOfAction inhibits protein synthesis
gptkbp:meltingPoint 102-106°C
gptkbp:molecularWeight 480.64 g/mol
gptkbp:origin Cephaelis ipecacuanha
gptkbp:PubChem_CID gptkb:CHEMBL1200692
10221
9802
gptkbp:routeOfAdministration oral
intramuscular
gptkbp:sideEffect nausea
vomiting
cardiotoxicity
gptkbp:solubility slightly soluble in water
soluble in alcohol
gptkbp:toxicity cardiotoxic
gptkbp:UNII 6T8X9E0653
gptkbp:usedFor treatment of amoebiasis
gptkbp:bfsParent gptkb:Ipecacuanha
gptkb:isoquinoline_alkaloids
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label emetine