duloxetine hydrochloride

GPTKB entity

Statements (42)
Predicate Object
gptkbp:instanceOf gptkb:drug
norepinephrine reuptake inhibitor
gptkbp:approvalYear 2004
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode gptkb:N06AX21
gptkbp:brand gptkb:Cymbalta
Yentreve
gptkbp:CASNumber gptkb:136434-34-9
gptkbp:chemicalFormula C18H19NOS·HCl
gptkbp:contraindication concurrent use with MAO inhibitors
uncontrolled narrow-angle glaucoma
gptkbp:developedBy gptkb:Eli_Lilly_and_Company
gptkbp:drugClass analgesic
benzodiazepine
antidepressant
gptkbp:eliminationHalfLife 12 hours
gptkbp:excretion urine
feces
https://www.w3.org/2000/01/rdf-schema#label duloxetine hydrochloride
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction inhibits reuptake of serotonin and norepinephrine
gptkbp:metabolism liver
gptkbp:molecularWeight 333.88 g/mol
gptkbp:pregnancyCategory gptkb:D_(Australia)
C (US)
gptkbp:proteinBinding 96%
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
constipation
fatigue
drowsiness
dry mouth
increased sweating
gptkbp:synonym gptkb:LY248686
gptkb:duloxetine
gptkbp:usedFor gptkb:generalized_anxiety_disorder
gptkb:major_depressive_disorder
fibromyalgia
chronic musculoskeletal pain
diabetic peripheral neuropathic pain
gptkbp:bfsParent gptkb:Cymbalta
gptkbp:bfsLayer 6