|
gptkbp:instanceOf
|
gptkb:drug
alkaloid
|
|
gptkbp:approvedBy
|
gptkb:FDA
1946
|
|
gptkbp:ATCCode
|
N02CA01
|
|
gptkbp:brand
|
D.H.E. 45
Migranal
|
|
gptkbp:CASNumber
|
511-12-6
|
|
gptkbp:contraindication
|
pregnancy
coronary artery disease
uncontrolled hypertension
|
|
gptkbp:discoveredBy
|
gptkb:Sandoz_Laboratories
|
|
gptkbp:eliminationHalfLife
|
10 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:hasMolecularFormula
|
C33H37N5O5
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dihydroergotamine
|
|
gptkbp:isomerOf
|
gptkb:ergotamine
|
|
gptkbp:KEGGID
|
D07713
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
vasoconstrictor
serotonin receptor agonist
|
|
gptkbp:meltingPoint
|
210°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:origin
|
derived from ergot fungus
|
|
gptkbp:pregnancyCategory
|
X
|
|
gptkbp:PubChem_CID
|
10174
CHEMBL1201207
10613
DB00323
|
|
gptkbp:routeOfAdministration
|
intramuscular
subcutaneous
intravenous
intranasal
|
|
gptkbp:sideEffect
|
nausea
vomiting
dizziness
hypertension
|
|
gptkbp:synonym
|
gptkb:DHE
dihydroergotaminum
|
|
gptkbp:UNII
|
8Y164V895Y
|
|
gptkbp:usedFor
|
migraine treatment
cluster headache treatment
|
|
gptkbp:bfsParent
|
gptkb:Erythromycin
|
|
gptkbp:bfsLayer
|
5
|