|
gptkbp:instanceOf
|
gptkb:drug
nonsteroidal anti-inflammatory drug
|
|
gptkbp:activeIngredient
|
gptkb:diclofenac
|
|
gptkbp:ATCCode
|
gptkb:M01AB05
|
|
gptkbp:availableOn
|
gptkb:tablet
injection
gel
suppository
eye drops
|
|
gptkbp:brand
|
gptkb:Voltaren
gptkb:Cataflam
gptkb:Zipsor
gptkb:Zorvolex
|
|
gptkbp:CASNumber
|
15307-79-6
|
|
gptkbp:contraindication
|
gptkb:asthma_(NSAID-induced)
peptic ulcer
severe heart failure
hypersensitivity to diclofenac
|
|
gptkbp:discoveredBy
|
gptkb:Ciba-Geigy
|
|
gptkbp:eliminationHalfLife
|
1-2 hours
|
|
gptkbp:excretion
|
gptkb:kidney
bile
|
|
gptkbp:hasMolecularFormula
|
C14H10Cl2NNaO2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
diclofenac sodium
|
|
gptkbp:introducedIn
|
1973
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
COX inhibitor
prostaglandin synthesis inhibitor
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
318.13 g/mol
|
|
gptkbp:pregnancyCategory
|
C (first and second trimester)
D (third trimester)
|
|
gptkbp:routeOfAdministration
|
oral
topical
intramuscular
rectal
ophthalmic
|
|
gptkbp:sideEffect
|
nausea
dizziness
headache
rash
elevated liver enzymes
gastrointestinal upset
|
|
gptkbp:usedFor
|
osteoarthritis
pain relief
inflammation
rheumatoid arthritis
migraine
ankylosing spondylitis
dysmenorrhea
|
|
gptkbp:bfsParent
|
gptkb:Voltaren
|
|
gptkbp:bfsLayer
|
5
|