Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
small molecule |
| gptkbp:CASNumber |
1073154-85-4
|
| gptkbp:clinicalTrialPhase |
Phase II
|
| gptkbp:developedBy |
Verastem Oncology
|
| gptkbp:hasInChIKey |
QJQYQKZQJZJZQJ-UHFFFAOYSA-N
|
| gptkbp:hasMolecularFormula |
C21H21FN6O
|
| gptkbp:hasSMILES |
C1=CC(=CC=C1CN2C=NC3=C2N=CN=C3NC4=CC=C(C=C4)F)C(=O)N
|
| gptkbp:hasUNII |
6Z1Y2V4S2E
|
| https://www.w3.org/2000/01/rdf-schema#label |
defactinib
|
| gptkbp:investigatedBy |
gptkb:non-small_cell_lung_cancer
gptkb:cancer mesothelioma |
| gptkbp:mechanismOfAction |
FAK inhibitor
|
| gptkbp:molecularWeight |
392.43 g/mol
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL2105728
25154815 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:synonym |
PF-04554878
VS-6063 |
| gptkbp:target |
focal adhesion kinase
|
| gptkbp:bfsParent |
gptkb:Verastem
|
| gptkbp:bfsLayer |
6
|