|
gptkbp:instanceOf
|
gptkb:chemical_compound
antineoplastic agent
|
|
gptkbp:approvalYear
|
1975
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
L01AX04
|
|
gptkbp:CASNumber
|
4342-03-4
|
|
gptkbp:category
|
antineoplastic and immunomodulating agent
|
|
gptkbp:chemicalFormula
|
C6H10N6O
|
|
gptkbp:color
|
white
|
|
gptkbp:discoveredBy
|
1960s
|
|
gptkbp:eliminationHalfLife
|
5 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dacarbazine
|
|
gptkbp:IUPACName
|
5-(3,3-dimethyl-1-triazenyl)imidazole-4-carboxamide
|
|
gptkbp:KEGGID
|
gptkb:D00293
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
DNA alkylation
|
|
gptkbp:MeSH_ID
|
D003615
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
182.18 g/mol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:PubChem_CID
|
4329
4179
CHEMBL1387
DB00851
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
nausea
vomiting
anorexia
myelosuppression
flu-like symptoms
|
|
gptkbp:solubility
|
soluble in water
|
|
gptkbp:storage
|
protect from light
|
|
gptkbp:synonym
|
gptkb:DIC
gptkb:DTIC
Imidazole carboxamide
|
|
gptkbp:UNII
|
6QXW8STU1B
|
|
gptkbp:usedFor
|
gptkb:Hodgkin's_lymphoma
malignant melanoma
|
|
gptkbp:bfsParent
|
gptkb:procarbazine
|
|
gptkbp:bfsLayer
|
7
|