Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
deoxyuridine 5'-triphosphate nucleotidohydrolase
deoxyuridine triphosphatase |
| gptkbp:biologicalProcess |
pyrimidine metabolism
|
| gptkbp:catalyzes |
hydrolysis of dUTP to dUMP and pyrophosphate
|
| gptkbp:cofactor |
Mg2+
|
| gptkbp:EC_number |
3.6.1.23
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
| gptkbp:function |
prevents incorporation of uracil into DNA
|
| gptkbp:gene |
gptkb:DUT
|
| https://www.w3.org/2000/01/rdf-schema#label |
dUTPase
|
| gptkbp:inhibitedBy |
dUDP
|
| gptkbp:locatedOnChromosome |
15q21.1
|
| gptkbp:molecular_function_(GO) |
dUTP diphosphatase activity
|
| gptkbp:PDB |
1Q5H
|
| gptkbp:product |
dUMP
pyrophosphate |
| gptkbp:role_in_DNA_metabolism |
maintains low intracellular dUTP levels
|
| gptkbp:role_in_DNA_repair |
prevents uracil misincorporation
|
| gptkbp:structure |
homotrimer in many species
|
| gptkbp:substrate |
gptkb:dUTP
|
| gptkbp:UniProtID |
P33316
|
| gptkbp:bfsParent |
gptkb:dUTP
|
| gptkbp:bfsLayer |
7
|