Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:associatedWith |
deoxycytidine analog metabolism
drug resistance in cancer therapy |
| gptkbp:catalyzes |
deamination of cytidine to uridine
deamination of deoxycytidine to deoxyuridine |
| gptkbp:cofactor |
zinc
|
| gptkbp:EC_number |
3.5.4.5
|
| gptkbp:expressedIn |
liver
spleen bone marrow |
| gptkbp:foundIn |
gptkb:Bacteria
humans mammals |
| gptkbp:function |
regulation of pyrimidine pool
|
| gptkbp:gene |
gptkb:CDA
|
| gptkbp:HGNC_ID |
1723
|
| https://www.w3.org/2000/01/rdf-schema#label |
cytidine deaminase
|
| gptkbp:inhibitedBy |
tetrahydrouridine
zebularine |
| gptkbp:involves |
nucleotide metabolism
pyrimidine salvage pathway |
| gptkbp:locatedOnChromosome |
gptkb:1p36.2
|
| gptkbp:molecularWeight |
16 kDa
|
| gptkbp:mutationAssociatedWith |
immunodeficiency (rare)
|
| gptkbp:OMIM |
608208
|
| gptkbp:PDB |
1MQ0
|
| gptkbp:product |
uridine
deoxyuridine |
| gptkbp:RefSeq_(human) |
NM_001785
|
| gptkbp:structure |
homotetramer (in humans)
|
| gptkbp:substrate |
cytidine
deoxycytidine |
| gptkbp:UniProtID |
P32320
|
| gptkbp:used_in |
biotechnology for base editing
|
| gptkbp:bfsParent |
gptkb:Gemcitabine
|
| gptkbp:bfsLayer |
7
|