|
gptkbp:instanceOf
|
progestin
antiandrogen
synthetic steroid
|
|
gptkbp:approvedBy
|
gptkb:Australia
gptkb:Canada
gptkb:France
gptkb:Germany
gptkb:United_Kingdom
|
|
gptkbp:ATCCode
|
gptkb:G03HA01
|
|
gptkbp:brand
|
gptkb:Androcur
gptkb:Diane-35
Climen
Cyprostat
Cyproteron
|
|
gptkbp:CASNumber
|
427-51-0
|
|
gptkbp:chemicalFormula
|
C24H29ClO4
|
|
gptkbp:compatibleWith
|
gptkb:United_States
|
|
gptkbp:contraindication
|
gptkb:liver_disease
pregnancy
history of meningioma
|
|
gptkbp:developedBy
|
gptkb:Schering_AG
|
|
gptkbp:discoveredBy
|
gptkb:Schering_AG
C. Elger
F. Neumann
K. Hauptmann
|
|
gptkbp:discoveredIn
|
1961
|
|
gptkbp:eliminationHalfLife
|
1.6–4.3 days
|
|
gptkbp:excretion
|
urine
feces
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cyproterone acetate
|
|
gptkbp:KEGGID
|
D07702
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1973
|
|
gptkbp:mechanismOfAction
|
androgen receptor antagonist
progestogenic activity
suppression of gonadotropins
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
416.94 g/mol
|
|
gptkbp:pregnancyCategory
|
X
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1423
5280980
4445392
DB04839
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular injection
|
|
gptkbp:sideEffect
|
gptkb:depression
fatigue
decreased libido
liver toxicity
gynecomastia
menstrual irregularities
|
|
gptkbp:UNII
|
8B1QWR724A
|
|
gptkbp:usedFor
|
treatment of prostate cancer
treatment of hirsutism
treatment of androgen-dependent conditions
treatment of hypersexuality
treatment of precocious puberty
treatment of severe acne
treatment of transgender hormone therapy
|
|
gptkbp:bfsParent
|
gptkb:Androgen_receptor
gptkb:Androcur
gptkb:Diane-35
|
|
gptkbp:bfsLayer
|
7
|