cyclobenzaprine

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:drug
muscle relaxant
gptkbp:approvedBy 1977
gptkbp:ATCCode M03BX08
gptkbp:availableOn gptkb:tablet
extended-release capsule
gptkbp:brand gptkb:Amrix
gptkb:Fexmid
gptkb:Flexeril
gptkbp:CASNumber 303-53-7
gptkbp:chemicalFormula C20H21N
gptkbp:contraindication gptkb:arrhythmias
MAOI use
heart block
hyperthyroidism
gptkbp:discoveredBy gptkb:Merck_&_Co.
gptkbp:drugClass tricyclic antidepressant derivative
gptkbp:eliminationHalfLife 18 hours
gptkbp:excretion urine
gptkbp:FDAApproved yes
https://www.w3.org/2000/01/rdf-schema#label cyclobenzaprine
gptkbp:interactsWith gptkb:beer
gptkb:CNS_depressants
gptkb:tramadol
serotonergic drugs
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction centrally acting skeletal muscle relaxant
gptkbp:metabolism liver
gptkbp:molecularWeight 275.39 g/mol
gptkbp:notRecommendedFor children under 15
long-term use
gptkbp:overdoseSymptoms cardiac arrest
seizures
tachycardia
gptkbp:pregnancyCategory B (US)
gptkbp:prescribes short-term use
gptkbp:prescriptionStatus Rx only (US)
gptkbp:PubChem_CID 2773
2673
gptkbp:relatedTo gptkb:amitriptyline
gptkbp:routeOfAdministration oral
gptkbp:sideEffect dizziness
fatigue
drowsiness
dry mouth
gptkbp:UNII 69Z37GR0UP
gptkbp:usedFor muscle spasms
musculoskeletal pain
gptkbp:bfsParent gptkb:Muscle_Relaxants,_Central
gptkbp:bfsLayer 7