coenzyme A

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:coenzyme
gptkbp:abbreviation gptkb:CoA
gptkbp:biosynthesized_from gptkb:ATP
cysteine
pantothenic acid
gptkbp:category gptkb:coenzyme
organophosphate
nucleotide derivative
thioester
gptkbp:chemicalFormula C21H36N7O16P3S
gptkbp:contains gptkb:adenosine
pantothenic acid
phosphate groups
beta-mercaptoethylamine
gptkbp:database_identifier_(CAS) 85-61-0
gptkbp:database_identifier_(ChEBI) gptkb:CHEBI:15346
gptkbp:database_identifier_(ChEMBL) CHEMBL1132
gptkbp:database_identifier_(DrugBank) DB01907
gptkbp:database_identifier_(HMDB) HMDB0001423
gptkbp:database_identifier_(KEGG) C00010
gptkbp:database_identifier_(MeSH) D003059
gptkbp:database_identifier_(PDB_Ligand) COA
gptkbp:database_identifier_(PubChem) 6815
gptkbp:database_identifier_(UNII) F82F2CKD89
gptkbp:degradation_product adenosine 3',5'-diphosphate
pantetheine
gptkbp:discoveredBy gptkb:Fritz_Lipmann
gptkbp:discoveredIn 1946
gptkbp:form gptkb:malonyl-CoA
gptkb:succinyl-CoA
acetyl-CoA
fatty acyl-CoA
thioesters
gptkbp:foundIn all living cells
https://www.w3.org/2000/01/rdf-schema#label coenzyme A
gptkbp:involves gptkb:pyruvate_dehydrogenase_complex
amino acid metabolism
citric acid cycle
fatty acid metabolism
gptkbp:IUPACName 3′-phosphoadenosine-5′-diphosphate-pantetheine
gptkbp:molecularWeight 767.53 g/mol
gptkbp:predecessor gptkb:pantothenic_acid_(vitamin_B5)
gptkbp:requires synthesis and oxidation of fatty acids
oxidation of pyruvate in the citric acid cycle
gptkbp:role gptkb:coenzyme
metabolism
acyl group carrier
gptkbp:solubility water soluble
gptkbp:structure thiol group
gptkbp:bfsParent gptkb:succinyl-CoA
gptkbp:bfsLayer 6