claudin-1

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:CLDN1
senescence-associated epithelial membrane protein
gptkbp:associatedWith hepatitis C virus entry
skin barrier function
gptkbp:discoveredIn 1998
gptkbp:encodedBy CLDN1 gene
gptkbp:expressedIn endothelial cells
epithelial cells
gptkbp:foundIn tight junctions
gptkbp:function regulates paracellular permeability
maintains cell polarity
https://www.w3.org/2000/01/rdf-schema#label claudin-1
gptkbp:locale gptkb:plasma_membrane
gptkbp:locatedOnChromosome chromosome 3q28-q29
gptkbp:molecularWeight 23 kDa
gptkbp:mutationAssociatedWith neonatal ichthyosis-sclerosing cholangitis syndrome
gptkbp:organism gptkb:Homo_sapiens
gptkbp:relatedTo claudin family
gptkbp:structure four transmembrane domains
gptkbp:UniProtID O95832
gptkbp:bfsParent gptkb:CLDN1
gptkbp:bfsLayer 7