Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
bleeding disorder |
| gptkbp:affects |
mostly males
|
| gptkbp:alsoKnownAs |
gptkb:hemophilia_A
|
| gptkbp:causedBy |
deficiency of factor VIII
|
| gptkbp:complication |
gptkb:anemia
hemarthrosis intracranial hemorrhage |
| gptkbp:diagnosedBy |
factor VIII assay
|
| gptkbp:firstDescribed |
1803
|
| gptkbp:gene |
gptkb:F8
|
| https://www.w3.org/2000/01/rdf-schema#label |
classic hemophilia
|
| gptkbp:ICD-10_code |
D66
|
| gptkbp:inheritance |
X-linked recessive
|
| gptkbp:notableCase |
European royal families
|
| gptkbp:OMIM |
306700
|
| gptkbp:prevalence |
1 in 5,000 male births
|
| gptkbp:riskFactor |
family history of hemophilia
|
| gptkbp:symptom |
prolonged bleeding
spontaneous joint bleeding |
| gptkbp:treatment |
factor VIII replacement therapy
|
| gptkbp:bfsParent |
gptkb:Hemophilia_A
|
| gptkbp:bfsLayer |
7
|