|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:parathyroid_secretory_protein_1
CgA
|
|
gptkbp:clinicalTrialPhase
|
serum chromogranin-A test
|
|
gptkbp:degradedBy
|
proteolytic enzymes
|
|
gptkbp:diagnosedBy
|
gptkb:pheochromocytoma
gptkb:carcinoid_tumors
neuroendocrine tumors
|
|
gptkbp:discoveredIn
|
1967
|
|
gptkbp:elevatedIn
|
gptkb:chronic_atrophic_gastritis
heart failure
proton pump inhibitor use
renal insufficiency
|
|
gptkbp:encodedBy
|
gptkb:CHGA_gene
|
|
gptkbp:expressedIn
|
gptkb:pituitary_gland
gptkb:pancreatic_islets
gptkb:adrenal_medulla
gastrointestinal tract
parathyroid gland
sympathetic neurons
|
|
gptkbp:foundIn
|
gptkb:chromaffin_granules
neuroendocrine cells
|
|
gptkbp:function
|
precursor to biologically active peptides
regulation of secretory granule formation
|
|
gptkbp:HGNC_ID
|
1926
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
chromogranin-A
|
|
gptkbp:locatedOnChromosome
|
human chromosome 14q32.12
|
|
gptkbp:molecularWeight
|
~48 kDa
|
|
gptkbp:OMIM
|
118910
|
|
gptkbp:PDB
|
1M1J
|
|
gptkbp:predecessor
|
gptkb:parastatin
gptkb:catestatin
gptkb:pancreastatin
gptkb:vasostatin
serpinin
|
|
gptkbp:secretes
|
exocytosis
|
|
gptkbp:structure
|
acidic glycoprotein
|
|
gptkbp:UniProtID
|
P10645
|
|
gptkbp:usedAs
|
biomarker
|
|
gptkbp:bfsParent
|
gptkb:Chromogranin_A
|
|
gptkbp:bfsLayer
|
6
|