|
gptkbp:instanceOf
|
gptkb:drug
bile acid sequestrant
|
|
gptkbp:approvedBy
|
gptkb:FDA
1960s
|
|
gptkbp:ATCCode
|
C10AC01
|
|
gptkbp:brand
|
gptkb:Locholest
gptkb:Prevalite
gptkb:Questran
|
|
gptkbp:CASNumber
|
11041-12-6
|
|
gptkbp:chemicalFormula
|
(C27H47N)(C2H4Cl)n
|
|
gptkbp:contraindication
|
complete biliary obstruction
hypersensitivity to cholestyramine
|
|
gptkbp:discoveredIn
|
1950s
|
|
gptkbp:eliminatedIn
|
fecal
|
|
gptkbp:essentialMedicine
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:form
|
powder for oral suspension
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cholestyramine
|
|
gptkbp:interactsWith
|
gptkb:warfarin
gptkb:digoxin
gptkb:thiazide_diuretics
thyroid hormones
fat-soluble vitamins
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
binds bile acids in the intestine
|
|
gptkbp:notAbsorbed
|
systemically
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
abdominal pain
constipation
bloating
flatulence
|
|
gptkbp:usedFor
|
gptkb:familial_hypercholesterolemia
diarrhea due to bile acid malabsorption
pruritus due to biliary obstruction
|
|
gptkbp:bfsParent
|
gptkb:levothyroxine_sodium
gptkb:L-thyroxine
|
|
gptkbp:bfsLayer
|
7
|