cholesterol 7 alpha-hydroxylase
GPTKB entity
Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:CYP7A1
cholest-5-en-3β-ol 7α-monooxygenase cytochrome P450 7A1 |
| gptkbp:biologicalProcess |
oxidoreductase activity
|
| gptkbp:catalyzes |
hydroxylation of cholesterol at 7-alpha position
|
| gptkbp:cofactor |
gptkb:cytochrome_P450_reductase
NADPH |
| gptkbp:EC_number |
1.14.14.23
|
| gptkbp:foundIn |
liver
|
| gptkbp:gene |
gptkb:CYP7A1
|
| https://www.w3.org/2000/01/rdf-schema#label |
cholesterol 7 alpha-hydroxylase
|
| gptkbp:locatedIn |
gptkb:endoplasmic_reticulum
|
| gptkbp:locatedOnChromosome |
chromosome 8q11-q12
|
| gptkbp:OMIM |
118485
|
| gptkbp:pathway |
bile acid biosynthesis
|
| gptkbp:regulates |
feedback inhibited by bile acids
|
| gptkbp:UniProtID |
gptkb:P22680
|
| gptkbp:bfsParent |
gptkb:CYP7A1
|
| gptkbp:bfsLayer |
6
|