Statements (62)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
6
|
| gptkbp:bfsParent |
gptkb:Vibrio_cholerae
|
| gptkbp:affects |
intestinal epithelial cells
|
| gptkbp:can_lead_to |
fluid secretion
|
| gptkbp:caused_by |
dehydration
severe diarrhea |
| gptkbp:combatants |
G M1 ganglioside
|
| gptkbp:composed_of |
A and B subunits
|
| gptkbp:died_in |
high doses
|
| gptkbp:discovered_by |
gptkb:Robert_Koch
|
| gptkbp:established |
specific inhibitors
adenylate cyclase |
| gptkbp:focuses_on |
epidemiological studies
public health interventions public health studies infectious disease research vaccine research |
| gptkbp:game_components |
cholera vaccines
|
| gptkbp:has_ability |
monoclonal antibodies
|
| https://www.w3.org/2000/01/rdf-schema#label |
cholera toxin
|
| gptkbp:increased |
c AMP levels
|
| gptkbp:is_associated_with |
waterborne diseases
acute gastroenteritis cholera disease enterotoxigenic effects |
| gptkbp:is_enhanced_by |
gptkb:monoclonal_antibody
|
| gptkbp:is_involved_in |
cell signaling
signal transduction pathways pathophysiological processes |
| gptkbp:is_known_for |
alter ion transport
disrupt cellular homeostasis induce apoptosis in cells stimulate fluid secretion |
| gptkbp:is_linked_to |
epidemics of cholera
|
| gptkbp:is_studied_in |
toxicology
mechanism of action |
| gptkbp:is_used_for |
molecular adjuvant
|
| gptkbp:is_used_in |
research and vaccine development
|
| gptkbp:key |
cholera treatment strategies
|
| gptkbp:notable_recipients |
cholera morbidity and mortality
|
| gptkbp:participated_in |
immune response
|
| gptkbp:produced_by |
gptkb:Vibrio_cholerae
laboratory conditions infection with Vibrio cholerae |
| gptkbp:recognizes |
immunoassays
|
| gptkbp:related_model |
studying other toxins
|
| gptkbp:risk_factor |
gptkb:Vibrio_cholerae
|
| gptkbp:scientific_classification |
a bacterial toxin
|
| gptkbp:subject |
biomedical research
clinical studies molecular biology studies toxin research toxin-antitoxin studies toxinology |
| gptkbp:targets |
therapeutic interventions
diagnostic tests antitoxin therapies |
| gptkbp:thermal_design_power |
in nature
|
| gptkbp:type_of |
AB toxin
|
| gptkbp:was_a_factor_in |
fluid loss
cholera pathogenesis |