ceftaroline fosamil acetate

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:antibiotic gptkb:cephalosporin
gptkbp:activeIngredient	gptkb:ceftaroline
gptkbp:administeredBy	intravenous infusion
gptkbp:approvedBy	gptkb:FDA
gptkbp:ATCCode	J01DI02
gptkbp:CASNumber	866021-55-6
gptkbp:contraindication	hypersensitivity to cephalosporins
gptkbp:developedBy	gptkb:Forest_Laboratories
gptkbp:effect	gptkb:methicillin-resistant_Staphylococcus_aureus
gptkbp:eliminationHalfLife	2.6 hours
gptkbp:excretion	renal
gptkbp:hasMolecularFormula	C22H21N8O8PS4
gptkbp:legalStatus	prescription only
gptkbp:mechanismOfAction	inhibits bacterial cell wall synthesis
gptkbp:metabolism	hydrolysis to ceftaroline
gptkbp:pregnancyCategory	B (US)
gptkbp:prodrugOf	gptkb:ceftaroline
gptkbp:proteinBinding	20%
gptkbp:routeOfAdministration	intravenous
gptkbp:sideEffect	nausea diarrhea headache rash
gptkbp:spectrumOfActivity	Gram-negative bacteria Gram-positive bacteria
gptkbp:usedFor	gptkb:community-acquired_bacterial_pneumonia bacterial infections acute bacterial skin and skin structure infections
gptkbp:bfsParent	gptkb:ceftaroline
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	ceftaroline fosamil acetate