ceftaroline fosamil acetate

URI: https://gptkb.org/entity/ceftaroline_fosamil_acetate
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:antibiotic
cephalosporin
gptkbp:activeIngredient gptkb:ceftaroline
gptkbp:administeredBy intravenous infusion
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode J01DI02
gptkbp:CASNumber 866021-55-6
gptkbp:contraindication hypersensitivity to cephalosporins
gptkbp:developedBy gptkb:Forest_Laboratories
gptkbp:effect gptkb:methicillin-resistant_Staphylococcus_aureus
gptkbp:eliminationHalfLife 2.6 hours
gptkbp:excretion renal
gptkbp:hasMolecularFormula C22H21N8O8PS4
https://www.w3.org/2000/01/rdf-schema#label ceftaroline fosamil acetate
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction inhibits bacterial cell wall synthesis
gptkbp:metabolism hydrolysis to ceftaroline
gptkbp:pregnancyCategory B (US)
gptkbp:prodrugOf gptkb:ceftaroline
gptkbp:proteinBinding 20%
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect nausea
diarrhea
headache
rash
gptkbp:spectrumOfActivity Gram-negative bacteria
Gram-positive bacteria
gptkbp:usedFor gptkb:community-acquired_bacterial_pneumonia
bacterial infections
acute bacterial skin and skin structure infections
gptkbp:bfsParent gptkb:ceftaroline
gptkbp:bfsLayer 7