|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:carbonate_dehydratase_II
CA-II
|
|
gptkbp:associatedWith
|
gptkb:osteopetrosis
renal tubular acidosis
|
|
gptkbp:cofactor
|
zinc
|
|
gptkbp:discoveredBy
|
Erling H. Christiansen
|
|
gptkbp:discoveredIn
|
1932
|
|
gptkbp:EC_number
|
4.2.1.1
|
|
gptkbp:family
|
gptkb:carbonic_anhydrase_family
|
|
gptkbp:function
|
catalyzes the reversible hydration of carbon dioxide
|
|
gptkbp:gene
|
gptkb:CA2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
carbonic anhydrase II
|
|
gptkbp:inhibitedBy
|
gptkb:acetazolamide
gptkb:brinzolamide
gptkb:methazolamide
gptkb:dorzolamide
|
|
gptkbp:locatedOnChromosome
|
8q21.2
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
29 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1CA2
|
|
gptkbp:product
|
gptkb:proton
bicarbonate
|
|
gptkbp:structure
|
monomeric protein
|
|
gptkbp:substrate
|
gptkb:water
carbon dioxide
|
|
gptkbp:tissue_specificity
|
gptkb:kidney
gastrointestinal tract
high in red blood cells
|
|
gptkbp:UniProtID
|
P00918
|
|
gptkbp:bfsParent
|
gptkb:1UU3
gptkb:3OMV
gptkb:1RY7
gptkb:2Q9V
|
|
gptkbp:bfsLayer
|
7
|