| 
                                    
                                        gptkbp:instanceOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:drug
                                        
                                         
                                    
                                        
                                            gptkb:opioid
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:approvedBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            1978
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:ATCCode
                                    
                                 | 
                                
                                    
                                        
                                            
                                            N02AF01
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:availableOn
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:nasal_spray
                                        
                                         
                                    
                                        
                                            
                                            injectable solution
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:brand
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Stadol
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:CASNumber
                                    
                                 | 
                                
                                    
                                        
                                            
                                            42408-82-2
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:cause
                                    
                                 | 
                                
                                    
                                        
                                            
                                            withdrawal symptoms
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:chemicalFormula
                                    
                                 | 
                                
                                    
                                        
                                            
                                            C21H29NO2
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:contraindication
                                    
                                 | 
                                
                                    
                                        
                                            
                                            respiratory depression
                                        
                                        
                                         
                                    
                                        
                                            
                                            hypersensitivity to butorphanol
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:controlledSubstanceSchedule
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Schedule IV (US)
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:developedBy
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Bristol-Myers_Squibb
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:eliminationHalfLife
                                    
                                 | 
                                
                                    
                                        
                                            
                                            5-6 hours
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:excretion
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:kidney
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:has_stereochemistry
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:levorphanol
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:interactsWith
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:beer
                                        
                                         
                                    
                                        
                                            gptkb:CNS_depressants
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:isSynthetic
                                    
                                 | 
                                
                                    
                                        
                                            
                                            true
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:legalStatus
                                    
                                 | 
                                
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:mechanismOfAction
                                    
                                 | 
                                
                                    
                                        
                                            
                                            partial agonist at mu-opioid receptor
                                        
                                        
                                         
                                    
                                        
                                            
                                            agonist at kappa-opioid receptor
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:metabolism
                                    
                                 | 
                                
                                    
                                        
                                            
                                            liver
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:molecularWeight
                                    
                                 | 
                                
                                    
                                        
                                            
                                            327.46 g/mol
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:notRecommendedFor
                                    
                                 | 
                                
                                    
                                        
                                            
                                            children under 18
                                        
                                        
                                         
                                    
                                        
                                            
                                            patients with head injury
                                        
                                        
                                         
                                    
                                        
                                            
                                            patients with severe asthma
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:pregnancyCategory
                                    
                                 | 
                                
                                    
                                        
                                            
                                            C (US)
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:PubChem_CID
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:DB00619
                                        
                                         
                                    
                                        
                                            
                                            60953
                                        
                                        
                                         
                                    
                                        
                                            
                                            CHEMBL1201207
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:riskFactor
                                    
                                 | 
                                
                                    
                                        
                                            
                                            potential for abuse
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:routeOfAdministration
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:nasal_spray
                                        
                                         
                                    
                                        
                                            
                                            intramuscular
                                        
                                        
                                         
                                    
                                        
                                            
                                            intravenous
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:sideEffect
                                    
                                 | 
                                
                                    
                                        
                                            
                                            nausea
                                        
                                        
                                         
                                    
                                        
                                            
                                            dizziness
                                        
                                        
                                         
                                    
                                        
                                            
                                            sweating
                                        
                                        
                                         
                                    
                                        
                                            
                                            respiratory depression
                                        
                                        
                                         
                                    
                                        
                                            
                                            sedation
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:UNII
                                    
                                 | 
                                
                                    
                                        
                                            
                                            YO3Y2D6FTW
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:usedFor
                                    
                                 | 
                                
                                    
                                        
                                            
                                            pain management
                                        
                                        
                                         
                                    
                                        
                                            
                                            migraine treatment
                                        
                                        
                                         
                                    
                                        
                                            
                                            labor pain
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsParent
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:dextrorphan
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsLayer
                                    
                                 | 
                                
                                    
                                        
                                            
                                            7
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        https://www.w3.org/2000/01/rdf-schema#label
                                    
                                 | 
                                
                                    
                                        
                                            
                                            butorphanol
                                        
                                        
                                         
                                    
                                 |