busulfan

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
antineoplastic agent
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode L01AB01
gptkbp:brand gptkb:Busulfex
gptkb:Myleran
gptkbp:CASNumber 55-98-1
gptkbp:chemicalFormula C6H14O6S2
gptkbp:discoveredBy 1950s
gptkbp:excretion gptkb:kidney
gptkbp:hasSMILES O=S(=O)(OCCOCCOCCOS(=O)(=O)C)C
https://www.w3.org/2000/01/rdf-schema#label busulfan
gptkbp:legalStatus prescription only
gptkbp:meltingPoint 103-105 °C
gptkbp:MeSH_ID gptkb:D002052
gptkbp:metabolism liver
gptkbp:molecularWeight 246.3 g/mol
gptkbp:pregnancyCategory D (US)
gptkbp:PubChem_CID gptkb:CHEMBL608
gptkb:DB01008
2476
gptkbp:routeOfAdministration oral
intravenous
gptkbp:sideEffect pulmonary fibrosis
seizures
myelosuppression
hyperpigmentation
gptkbp:UNII G1LN9045DK
gptkbp:usedFor conditioning regimen before bone marrow transplantation
treatment of chronic myelogenous leukemia
gptkbp:bfsParent gptkb:multidrug_resistance-associated_protein_1
gptkbp:bfsLayer 6