Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:beta_blocker
gptkb:drug |
| gptkbp:approvedBy |
1986
|
| gptkbp:ATCCode |
C07AB07
|
| gptkbp:brand |
gptkb:Concor
Zebeta |
| gptkbp:CASNumber |
66722-44-9
|
| gptkbp:chemicalClass |
gptkb:phenylethanolamine
|
| gptkbp:contraindication |
severe bradycardia
cardiogenic shock severe asthma |
| gptkbp:discoveredBy |
gptkb:Merck
|
| gptkbp:eliminationHalfLife |
10-12 hours
|
| gptkbp:excretion |
gptkb:kidney
|
| gptkbp:hasMolecularFormula |
C18H31NO4
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
selective beta-1 adrenergic receptor blocker
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C (US)
B3 (Australia) |
| gptkbp:proteinBinding |
30%
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
dizziness
fatigue hypotension bradycardia |
| gptkbp:UNII |
Y41JS2NL6U
|
| gptkbp:usedFor |
heart failure
hypertension angina pectoris |
| gptkbp:bfsParent |
gptkb:Beta-1_adrenergic_receptor
gptkb:ADRB1 gptkb:Коронал gptkb:Hydrochlorothiazide |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
bisoprolol
|