Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:antibiotic antineoplastic agent |
| gptkbp:CASNumber |
115-02-6
|
| gptkbp:chemicalFormula |
C5H7N3O4
|
| gptkbp:discoveredBy |
1950s
|
| https://www.w3.org/2000/01/rdf-schema#label |
azaserine
|
| gptkbp:IUPACName |
(S)-2-amino-3-(hydroxyamino)propanoyl-L-serine
|
| gptkbp:mechanismOfAction |
inhibits nucleotide biosynthesis
inhibits purine biosynthesis inhibits pyrimidine biosynthesis |
| gptkbp:molecularWeight |
173.13 g/mol
|
| gptkbp:producedBy |
Streptomyces fragilis
|
| gptkbp:sideEffect |
nephrotoxicity
myelosuppression gastrointestinal toxicity |
| gptkbp:studiedBy |
cancer metabolism
biochemistry of nucleotide synthesis |
| gptkbp:usedFor |
inhibitor of glutamine amidotransferase
|
| gptkbp:bfsParent |
gptkb:GMP_synthetase
|
| gptkbp:bfsLayer |
7
|