|
gptkbp:instanceOf
|
gptkb:disease
gptkb:virus
|
|
gptkbp:affects
|
birds
humans
|
|
gptkbp:alternativeName
|
gptkb:bird_flu
highly pathogenic avian influenza (HPAI) H5N1
|
|
gptkbp:causedBy
|
influenza A virus subtype H5N1
|
|
gptkbp:diagnosedBy
|
gptkb:RT-PCR
serology
virus isolation
|
|
gptkbp:discoveredBy
|
gptkb:China
1996
|
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gptkbp:family
|
gptkb:Orthomyxoviridae
|
|
gptkbp:genomeType
|
single-stranded RNA
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
avian influenza A (H5N1)
|
|
gptkbp:monitors
|
gptkb:World_Health_Organization
gptkb:Food_and_Agriculture_Organization
gptkb:OIE_(World_Organisation_for_Animal_Health)
|
|
gptkbp:mortalityRate
|
high
|
|
gptkbp:mutationAssociatedWith
|
neuraminidase (N1)
hemagglutinin (H5)
|
|
gptkbp:notableCaseFatalityRate
|
>50% in reported human cases
|
|
gptkbp:notableOutbreaks
|
gptkb:1997_Hong_Kong_outbreak
2003–2004 Southeast Asia outbreak
|
|
gptkbp:order
|
gptkb:Articulavirales
|
|
gptkbp:pandemicPotential
|
yes
|
|
gptkbp:prevention
|
biosecurity measures
vaccination (in poultry)
|
|
gptkbp:range
|
wild birds
domestic poultry
mammals (occasionally)
|
|
gptkbp:relatedTo
|
influenza pandemic preparedness
|
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gptkbp:riskFactor
|
high mortality rate
severe illness
|
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gptkbp:spreadTo
|
migratory birds
poultry trade
|
|
gptkbp:symptom
|
fever
respiratory distress
cough
muscle aches
sore throat
|
|
gptkbp:transmission
|
contact with infected birds
contaminated environments
|
|
gptkbp:treatment
|
antiviral drugs
|
|
gptkbp:vaccineAvailable
|
for poultry
experimental for humans
|
|
gptkbp:WHOConcernLevel
|
high
|
|
gptkbp:zoonotic
|
true
|
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gptkbp:bfsParent
|
gptkb:H5N1
|
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gptkbp:bfsLayer
|
5
|