aspartyl-tRNA synthetase

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:affiliatedWith aminoacyl-tRNA synthetase family
gptkbp:alternativeName gptkb:AspRS
aspartate--tRNA ligase
gptkbp:associatedWith hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL)
gptkbp:catalyzes attachment of aspartic acid to tRNA(Asp)
gptkbp:cellular_component_(GO) gptkb:cytoplasm
gptkbp:cofactor gptkb:ATP
gptkbp:EC_number 6.1.1.12
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:function protein biosynthesis
gptkbp:gene gptkb:DARS
gptkbp:gene_symbol_(E._coli) aspS
https://www.w3.org/2000/01/rdf-schema#label aspartyl-tRNA synthetase
gptkbp:molecular_function_(GO) aspartyl-tRNA ligase activity
gptkbp:product gptkb:AMP
gptkb:aspartyl-tRNA(Asp)
pyrophosphate
gptkbp:structure homodimer
gptkbp:substrate gptkb:tRNA(Asp)
aspartic acid
gptkbp:UniProt_ID_(E._coli) P00960
gptkbp:UniProtID Q15046
gptkbp:bfsParent gptkb:AspRS
gptkb:class_II_aminoacyl-tRNA_synthetase
gptkbp:bfsLayer 7