Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:ATP
|
| gptkbp:catalyzes |
carbamoyl phosphate + L-aspartate ⇌ phosphate + N-carbamoyl-L-aspartate
|
| gptkbp:cofactor |
none
|
| gptkbp:discoveredBy |
Yale University researchers
|
| gptkbp:EC_number |
2.1.3.2
|
| gptkbp:foundIn |
gptkb:Bacteria
|
| gptkbp:gene |
pyrB (in E. coli)
|
| https://www.w3.org/2000/01/rdf-schema#label |
aspartate transcarbamylase
|
| gptkbp:inhibitedBy |
gptkb:CTP
|
| gptkbp:involvedIn |
pyrimidine biosynthesis
|
| gptkbp:molecularWeight |
310 kDa (E. coli)
|
| gptkbp:PDB |
1RAA
|
| gptkbp:regulates |
allosteric
|
| gptkbp:structure |
dodecamer
|
| gptkbp:subunit |
6 catalytic subunits
6 regulatory subunits |
| gptkbp:bfsParent |
gptkb:CAD_gene
gptkb:Carbamoyl-phosphate_synthetase_2,_aspartate_transcarbamylase,_and_dihydroorotase_(CAD)_protein |
| gptkbp:bfsLayer |
8
|