Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:ARSB
gptkb:N-acetylgalactosamine-4-sulfatase |
| gptkbp:associatedWith |
gptkb:Maroteaux-Lamy_syndrome
|
| gptkbp:biologicalProcess |
glycosaminoglycan catabolic process
arylsulfatase activity |
| gptkbp:cellularComponent |
gptkb:lysosomal_lumen
|
| gptkbp:cofactor |
formylglycine
|
| gptkbp:deficiencyCauses |
gptkb:Mucopolysaccharidosis_type_VI
|
| gptkbp:EC_number |
3.1.6.12
|
| gptkbp:encodedBy |
gptkb:ARSB_gene
|
| gptkbp:function |
catalyzes the hydrolysis of sulfate esters from glycosaminoglycans
|
| gptkbp:locatedIn |
gptkb:lysosome
|
| gptkbp:locatedOnChromosome |
gptkb:5q14.1
|
| gptkbp:OMIM |
611542
|
| gptkbp:postTranslationalModification |
conversion of cysteine to formylglycine
|
| gptkbp:proteinFamily |
sulfatase family
|
| gptkbp:substrate |
dermatan sulfate
chondroitin sulfate |
| gptkbp:UniProtID |
gptkb:P15848
|
| gptkbp:bfsParent |
gptkb:ARSB
|
| gptkbp:bfsLayer |
7
|
| http://www.w3.org/2000/01/rdf-schema#label |
arylsulfatase B, lysosomal
|