artesunate-amodiaquine (ASAQ Winthrop)

URI: https://gptkb.org/entity/artesunate-amodiaquine_(ASAQ_Winthrop)
GPTKB entity
Statements (30)
Predicate Object
gptkbp:instanceOf antiviral drug
fixed-dose combination medication
gptkbp:activeIngredient gptkb:artesunate
gptkb:amodiaquine
gptkbp:approvedBy gptkb:World_Health_Organization
2007
gptkbp:ATCCode gptkb:P01BF05
gptkbp:contraindication history of hepatic impairment
history of neutropenia
hypersensitivity to amodiaquine
hypersensitivity to artesunate
gptkbp:developedBy Drugs for Neglected Diseases initiative (DNDi)
gptkbp:form gptkb:tablet
https://www.w3.org/2000/01/rdf-schema#label artesunate-amodiaquine (ASAQ Winthrop)
gptkbp:indication treatment of uncomplicated Plasmodium falciparum malaria
gptkbp:marketingAuthorizationHolder gptkb:Sanofi
gptkbp:mechanismOfAction inhibits parasite heme detoxification
produces free radicals toxic to malaria parasites
gptkbp:pregnancyCategory C
gptkbp:prescriptionStatus prescription only
gptkbp:routeOfAdministration oral
gptkbp:sideEffect gptkb:anemia
nausea
vomiting
liver enzyme elevation
gptkbp:usedIn gptkb:Africa
gptkb:Asia
gptkbp:WHOModelListOfEssentialMedicines included
gptkbp:bfsParent gptkb:Medicines_for_Malaria_Venture
gptkbp:bfsLayer 7