|
gptkbp:instanceOf
|
hormone
peptide
antidiuretic hormone
|
|
gptkbp:alternativeName
|
gptkb:vasopressin
gptkb:AVP
antidiuretic hormone
|
|
gptkbp:aminoAcidSequence
|
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
|
|
gptkbp:associatedWith
|
gptkb:diabetes_insipidus
gptkb:syndrome_of_inappropriate_antidiuretic_hormone_secretion
|
|
gptkbp:biosynthesisPrecursor
|
prepro-vasopressin
|
|
gptkbp:CASNumber
|
113-79-1
|
|
gptkbp:co-releasedWith
|
gptkb:oxytocin
|
|
gptkbp:discoveredBy
|
gptkb:Vincent_du_Vigneaud
|
|
gptkbp:discoveredIn
|
1953
|
|
gptkbp:disulfideBond
|
between Cys1 and Cys6
|
|
gptkbp:encodedBy
|
gptkb:AVP_gene
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:foundIn
|
mammals
|
|
gptkbp:function
|
vasoconstriction
increase blood pressure
regulation of water retention in kidneys
modulation of social behavior
|
|
gptkbp:halfLife
|
10-20 minutes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
arginine vasopressin
|
|
gptkbp:inhibitedBy
|
ethanol
|
|
gptkbp:medicalUse
|
treatment of diabetes insipidus
control of bleeding esophageal varices
management of vasodilatory shock
|
|
gptkbp:MeSH_ID
|
D014652
|
|
gptkbp:metabolism
|
gptkb:kidney
liver
|
|
gptkbp:producedBy
|
hypothalamus
|
|
gptkbp:promotion
|
gptkb:angiotensin_II
hypotension
hypovolemia
hyperosmolarity
|
|
gptkbp:PubChem_CID
|
CHEMBL1201280
DB00035
5362370
|
|
gptkbp:recipient
|
gptkb:V2_receptor
V1A receptor
V1B receptor
|
|
gptkbp:regulates
|
blood pressure
blood volume
plasma osmolality
|
|
gptkbp:releaseYear
|
posterior pituitary gland
|
|
gptkbp:structure
|
nonapeptide
|
|
gptkbp:UNII
|
Y49A2K43D6
|
|
gptkbp:bfsParent
|
gptkb:vasopressin
gptkb:vasopressin_receptors
gptkb:antidiuretic_hormone
|
|
gptkbp:bfsLayer
|
7
|