oxytocin

URI: https://gptkb.org/entity/oxytocin

GPTKB entity

Statements (60)

Predicate	Object
gptkbp:instanceOf	hormone peptide
gptkbp:administeredBy	intramuscular injection intravenous injection
gptkbp:approvedBy	gptkb:FDA
gptkbp:ATCCode	gptkb:H01BB02
gptkbp:CASNumber	50-56-6
gptkbp:category	peptide nonapeptide endocrine hormone labor-inducing agent lactation hormone social bonding hormone
gptkbp:chemicalFormula	C43H66N12O12S2
gptkbp:contraindication	gptkb:cephalopelvic_disproportion gptkb:fetal_distress unfavorable fetal position
gptkbp:discoveredBy	gptkb:Sir_Henry_Hallett_Dale
gptkbp:discoveredIn	1906
gptkbp:eliminatedIn	kidneys
gptkbp:firstSynthesized	gptkb:Vincent_du_Vigneaud
gptkbp:firstSynthesizedInYear	1953
gptkbp:foundIn	mammals
gptkbp:function	involved in sexual reproduction involved in social bonding regulates emotional responses stimulates milk ejection stimulates uterine contractions
gptkbp:gene	gptkb:OXT
gptkbp:halfLife	3-5 minutes
https://www.w3.org/2000/01/rdf-schema#label	oxytocin
gptkbp:IUPACName	(2S,5S,8S,11S,14S,17S,20S,23S,26S)-1,4,7,10,13,16,19,22,25-nonaazacyclohexacosan-2,5,8,11,14,17,20,23,26-nonone
gptkbp:legalStatus	prescription only
gptkbp:metabolism	liver
gptkbp:molecularWeight	1007.19 g/mol
gptkbp:NobelPrizeYear	Vincent du Vigneaud (1955, Chemistry)
gptkbp:pregnancyCategory	AU: A US: C
gptkbp:producedBy	hypothalamus
gptkbp:PubChem_CID	gptkb:CHEMBL3529 gptkb:DB00107 439302
gptkbp:recipient	gptkb:oxytocin_receptor
gptkbp:relatedTo	gptkb:vasopressin
gptkbp:releaseYear	posterior pituitary gland
gptkbp:routeOfAdministration	intramuscular intravenous nasal spray (experimental)
gptkbp:sideEffect	gptkb:uterine_hyperstimulation nausea vomiting hypotension
gptkbp:UNII	1J444QC288
gptkbp:usedFor	augmentation of labor control of postpartum bleeding facilitation of breastfeeding induction of labor
gptkbp:bfsParent	gptkb:pituitary_gland gptkb:hormone
gptkbp:bfsLayer	6