Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Dragon
|
| gptkbp:category |
mycotoxin
|
| gptkbp:chemicalClass |
peptide
|
| gptkbp:component |
gptkb:alpha-amanitin
gptkb:beta-amanitin gptkb:gamma-amanitin |
| gptkbp:discoveredBy |
gptkb:Heinrich_Wieland
|
| gptkbp:discoveredIn |
1941
|
| gptkbp:foundIn |
gptkb:Amanita_phalloides
gptkb:Amanita_virosa gptkb:Galerina_marginata Lepiota species |
| gptkbp:hasMolecularFormula |
C39H54N10O14 (alpha-amanitin)
|
| https://www.w3.org/2000/01/rdf-schema#label |
amatoxins
|
| gptkbp:LD50 |
~0.1 mg/kg (humans)
|
| gptkbp:mechanismOfAction |
inhibits RNA polymerase II
|
| gptkbp:routeOfExposure |
ingestion
|
| gptkbp:symptom |
nausea
vomiting diarrhea abdominal pain |
| gptkbp:toxicity |
kidney failure
liver failure highly toxic |
| gptkbp:treatment |
gptkb:penicillin_G
gptkb:silibinin supportive care liver transplantation activated charcoal |
| gptkbp:bfsParent |
gptkb:Fungi
|
| gptkbp:bfsLayer |
4
|