Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
acid alpha-glucosidase (for lysosomal form)
glucosidosucrase maltase neutral alpha-glucosidase |
| gptkbp:biologicalProcess |
glycoside hydrolase activity
|
| gptkbp:CASNumber |
9001-42-7
|
| gptkbp:catalyzes |
hydrolysis of alpha-glucosidic linkages
|
| gptkbp:deficiencyCauses |
gptkb:Pompe_disease
|
| gptkbp:EC_number |
3.2.1.20
|
| gptkbp:family |
gptkb:glycoside_hydrolase_family_31
|
| gptkbp:foundIn |
gptkb:yeast
gptkb:small_intestine plants |
| gptkbp:function |
breaks down starch and disaccharides to glucose
|
| gptkbp:gene |
GAA (for human acid alpha-glucosidase)
|
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-glucosidase
|
| gptkbp:inhibitedBy |
gptkb:acarbose
miglitol voglibose |
| gptkbp:locatedOnChromosome |
chromosome 17q25.3 (human GAA gene)
|
| gptkbp:optimum_pH |
5.0-6.8
|
| gptkbp:presentIn |
intestinal brush border
lysosome (acid alpha-glucosidase) |
| gptkbp:product |
glucose
|
| gptkbp:significance |
target for anti-diabetic drugs
|
| gptkbp:structure |
monomeric or dimeric protein
|
| gptkbp:substrate |
sucrose
maltose maltotriose |
| gptkbp:UniProtID |
P10253 (human acid alpha-glucosidase)
|
| gptkbp:usedFor |
type 2 diabetes (as a drug target)
|
| gptkbp:bfsParent |
gptkb:glycosidase
|
| gptkbp:bfsLayer |
7
|