|
gptkbp:instance_of
|
gptkb:protein
|
|
gptkbp:associated_with
|
neural tube defects
|
|
gptkbp:can
|
fetal abnormalities
|
|
gptkbp:can_be_used_to
|
monitoring treatment response
|
|
gptkbp:discovered_by
|
gptkb:Robert_W._K._Choi
|
|
gptkbp:first_introduced
|
clinical practice in the 1970s
|
|
gptkbp:function
|
binds to fatty acids
|
|
gptkbp:has_role
|
metabolism of lipids
|
|
gptkbp:has_sections
|
liver cancer
germ cell tumors
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
alpha-fetoprotein
|
|
gptkbp:influences
|
immune response
|
|
gptkbp:involved_in
|
angiogenesis
|
|
gptkbp:is_a
|
glycoprotein
|
|
gptkbp:is_associated_with
|
hepatitis
certain cancers
|
|
gptkbp:is_considered
|
a key biomarker
|
|
gptkbp:is_elevated_in
|
pregnancy
|
|
gptkbp:is_involved_in
|
cell differentiation
cell proliferation
|
|
gptkbp:is_linked_to
|
fetal health assessment
fetal liver function
|
|
gptkbp:is_monitored_by
|
treatment efficacy
|
|
gptkbp:is_part_of
|
maternal serum screening
|
|
gptkbp:is_recognized_as
|
gptkb:1956
|
|
gptkbp:is_regulated_by
|
hormones
|
|
gptkbp:is_tested_for
|
in prenatal screening
|
|
gptkbp:is_used_for
|
tumor marker
|
|
gptkbp:is_used_in
|
screening for testicular cancer
|
|
gptkbp:levels_decrease_after
|
birth
|
|
gptkbp:lifespan
|
5 days
|
|
gptkbp:may_be_elevated_in
|
certain liver diseases
|
|
gptkbp:may_be_lowered_in
|
certain genetic conditions
|
|
gptkbp:measures
|
blood tests
amniotic fluid
|
|
gptkbp:normal_range
|
0-10 ng/m L in adults
|
|
gptkbp:notable_for
|
high levels in fetuses
|
|
gptkbp:produced
|
pregnancy
|
|
gptkbp:produced_by
|
early pregnancy
embryonic tissues
fetal liver
|
|
gptkbp:promoter
|
AFP gene
|
|
gptkbp:reduces
|
gptkb:Down_syndrome
|
|
gptkbp:related_to
|
alpha-fetoprotein test
|
|
gptkbp:role
|
fetal development
|
|
gptkbp:security
|
fetal tissues
yolk sac
|
|
gptkbp:synthesized_by
|
liver cells
|
|
gptkbp:used_in
|
diagnosis of hepatocellular carcinoma
|
|
gptkbp:used_in_research_on
|
cancer biomarkers
|
|
gptkbp:used_to_monitor
|
liver disease
|
|
gptkbp:weight
|
approximately 70 k Da
|
|
gptkbp:when_elevated_can_indicate
|
malignancies
|
|
gptkbp:with_high_levels_can_lead_to
|
diagnostic procedures
|
|
gptkbp:bfsParent
|
gptkb:ADP-A2_AFP
gptkb:Embryonic_carcinoma
|
|
gptkbp:bfsLayer
|
7
|