Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:affiliatedWith |
aldo-keto reductase family
|
| gptkbp:alternativeName |
gptkb:ALR
Aldose reductase-like protein |
| gptkbp:associatedWith |
cataract formation
diabetic complications |
| gptkbp:biologicalProcess |
oxidoreductase activity
|
| gptkbp:CASNumber |
9028-97-1
|
| gptkbp:catalyzes |
reduction of aldehydes to alcohols
|
| gptkbp:cofactor |
gptkb:NADH
NADPH |
| gptkbp:EC_number |
1.1.1.21
|
| gptkbp:foundIn |
gptkb:kidney
liver human tissues lens of the eye |
| gptkbp:gene |
AKR1A1
|
| https://www.w3.org/2000/01/rdf-schema#label |
aldehyde reductase
|
| gptkbp:inhibitedBy |
quercetin
phenobarbital |
| gptkbp:involves |
detoxification of aldehydes
|
| gptkbp:locatedOnChromosome |
chromosome 1p34.1
|
| gptkbp:structure |
monomeric protein
|
| gptkbp:substrate |
aromatic aldehydes
aliphatic aldehydes glucose (minor activity) |
| gptkbp:UniProtID |
P14550
|
| gptkbp:bfsParent |
gptkb:Alcohol_dehydrogenase
|
| gptkbp:bfsLayer |
7
|