|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:AlaRS
gptkb:alanyl-tRNA_ligase
|
|
gptkbp:associatedWith
|
gptkb:Charcot-Marie-Tooth_disease
leukodystrophy
|
|
gptkbp:belongs_to_protein_family
|
gptkb:class_II_aminoacyl-tRNA_synthetase
|
|
gptkbp:catalyzes
|
attachment of alanine to tRNA(Ala)
|
|
gptkbp:cellular_component_(GO)
|
gptkb:cytoplasm
mitochondrion
|
|
gptkbp:EC_number
|
6.1.1.7
|
|
gptkbp:foundIn
|
gptkb:Bacteria
archaea
eukaryotes
|
|
gptkbp:function
|
aminoacylation of tRNA(Ala)
|
|
gptkbp:gene
|
gptkb:AARS1
|
|
gptkbp:gene_symbol_(mitochondrial,_human)
|
gptkb:AARS2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
alanyl-tRNA synthetase
|
|
gptkbp:molecular_function_(GO)
|
alanyl-tRNA ligase activity
|
|
gptkbp:participatedIn
|
translator
protein biosynthesis
|
|
gptkbp:product
|
gptkb:AMP
pyrophosphate
alanyl-tRNA(Ala)
|
|
gptkbp:requires
|
accurate translation of the genetic code
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:ATP
L-alanine
tRNA(Ala)
|
|
gptkbp:UniProt_ID_(mitochondrial,_human)
|
O43776
|
|
gptkbp:UniProtID
|
gptkb:P49588
|
|
gptkbp:bfsParent
|
gptkb:AARS
gptkb:class_II_aminoacyl-tRNA_synthetase
|
|
gptkbp:bfsLayer
|
7
|