gonadotropin-releasing hormone agonist
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
hormone agonist |
| gptkbp:actsOn |
gonadotropin-releasing hormone receptor
|
| gptkbp:administeredBy |
injection
nasal spray |
| gptkbp:cause |
initial hormone flare
|
| gptkbp:contraindication |
pregnancy
hypersensitivity to drug |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:example |
gptkb:goserelin
buserelin leuprolide nafarelin triptorelin |
| https://www.w3.org/2000/01/rdf-schema#label |
gonadotropin-releasing hormone agonist
|
| gptkbp:mechanismOfAction |
downregulation of pituitary gonadotropins
|
| gptkbp:regulates |
gptkb:follicle-stimulating_hormone
gptkb:luteinizing_hormone |
| gptkbp:sideEffect |
mood changes
hot flashes erectile dysfunction decreased bone density vaginal dryness |
| gptkbp:usedFor |
prostate cancer
endometriosis infertility treatment precocious puberty |
| gptkbp:bfsParent |
gptkb:Zoladex
|
| gptkbp:bfsLayer |
7
|