Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:activeIngredient |
gptkb:ceftolozane
tazobactam |
| gptkbp:approvalYear |
2014
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
J01DI54
|
| gptkbp:chemicalFormula |
C23H30N12O13S2 (ceftolozane), C10H12N4O5S (tazobactam)
|
| gptkbp:drugClass |
cephalosporin
beta-lactamase inhibitor |
| https://www.w3.org/2000/01/rdf-schema#label |
Zerbaxa
|
| gptkbp:indication |
hospital-acquired bacterial pneumonia
ventilator-associated bacterial pneumonia |
| gptkbp:legalStatus |
prescription only
|
| gptkbp:manufacturer |
gptkb:Merck_&_Co.
|
| gptkbp:mechanismOfAction |
inhibits bacterial cell wall synthesis
beta-lactamase inhibition |
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
fever
nausea diarrhea headache |
| gptkbp:usedFor |
complicated urinary tract infections
complicated intra-abdominal infections |
| gptkbp:bfsParent |
gptkb:MRK
|
| gptkbp:bfsLayer |
5
|