|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
AWT1
GLCL
NPHS4
WT33
Wilms tumor suppressor gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Wilms_tumor
gptkb:Denys-Drash_syndrome
Frasier syndrome
Meacham syndrome
|
|
gptkbp:clinicalTrialPhase
|
genetic testing for Wilms tumor risk
|
|
gptkbp:discoveredBy
|
David G. Haber
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodes
|
Wilms tumor protein
|
|
gptkbp:Entrez_Gene_ID
|
7490
|
|
gptkbp:expressedIn
|
gptkb:kidney
gonads
|
|
gptkbp:fullName
|
Wilms tumor 1 gene
|
|
gptkbp:function
|
tumor suppressor
transcription factor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
12796
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WT1 gene
|
|
gptkbp:length
|
10 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p13
chromosome 11
|
|
gptkbp:mutationAssociatedWith
|
genitourinary anomalies
pediatric kidney cancer
|
|
gptkbp:OMIM
|
607102
|
|
gptkbp:orthologInMouse
|
Wt1
|
|
gptkbp:product
|
WT1 protein
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:regulates
|
apoptosis
differentiation
cell growth
|
|
gptkbp:transcriptionVariants
|
multiple
|
|
gptkbp:UniProtID
|
P19544
|
|
gptkbp:bfsParent
|
gptkb:rhabdomyosarcoma
|
|
gptkbp:bfsLayer
|
5
|