Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Wilms_tumor
|
| gptkbp:affects |
increased cancer risk
psychosocial impact kidney function impairment |
| gptkbp:associated_with |
gptkb:nephroblastoma
endocrine disorders other syndromes congenital anomalies gonadal dysgenesis |
| gptkbp:caused_by |
gptkb:Wilms_tumor
nephropathy |
| gptkbp:clinical_trial |
pediatric oncology
ongoing research multidisciplinary approach failure to thrive hematuria pediatric nephrology investigating new therapies abdominal mass studying genetic factors |
| gptkbp:descendant |
autosomal dominant
|
| gptkbp:discovered_by |
gptkb:Denys-Drash
|
| gptkbp:events |
regular monitoring
management of kidney function screening for tumors |
| gptkbp:first_described_by |
1970s
|
| gptkbp:genetic_diversity |
recommended
important for families |
| gptkbp:historical_significance |
first described in 1967
|
| https://www.w3.org/2000/01/rdf-schema#label |
Denys-Drash syndrome
|
| gptkbp:is_characterized_by |
early onset kidney disease
genital abnormalities male pseudohermaphroditism |
| gptkbp:is_popular_in |
rare
|
| gptkbp:modifications |
W T1 gene
|
| gptkbp:related_to |
gptkb:DSS_syndrome
|
| gptkbp:research_focus |
improving treatment outcomes
identifying new mutations understanding W T1 gene function |
| gptkbp:risk_factor |
family history
genetic mutations |
| gptkbp:scholarships |
gptkb:Educational_Institution
support groups available resources |
| gptkbp:social_responsibility |
variable
genetic testing |
| gptkbp:symptoms |
hypertension
edema proteinuria |
| gptkbp:treatment |
gptkb:hospital
chemotherapy renal replacement therapy |