WD40-repeat proteins

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName WD-repeat proteins
beta-transducin repeat proteins
gptkbp:domain gptkb:WD40_repeat
gptkbp:example E3 ubiquitin ligase
Gβ subunit of heterotrimeric G proteins
Tup1 transcriptional corepressor
gptkbp:firstDescribed 1990s
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:function protein-protein interaction
https://www.w3.org/2000/01/rdf-schema#label WD40-repeat proteins
gptkbp:InterPro IPR001680
gptkbp:motif GH dipeptide
WD dipeptide
gptkbp:namedAfter tryptophan-aspartic acid (WD) dipeptide
gptkbp:number_of_repeats typically 4 to 16
gptkbp:Pfam_family PF00400
gptkbp:repeat_length ~40 amino acids
gptkbp:role apoptosis
signal transduction
gene regulation
chromatin modification
cell cycle control
vesicle formation
gptkbp:SCOP b.69
gptkbp:structure beta-propeller
gptkbp:bfsParent gptkb:CCT_(Complex_of_Chaperonins_Containing_TCP-1)
gptkbp:bfsLayer 7