|
gptkbp:instanceOf
|
gptkb:genetic_disorder
gptkb:disease
gptkb:bleeding_disorder
|
|
gptkbp:affects
|
blood clotting
both males and females
|
|
gptkbp:causedBy
|
deficiency of von Willebrand factor
dysfunction of von Willebrand factor
|
|
gptkbp:complication
|
gptkb:anemia
severe bleeding
|
|
gptkbp:diagnosedBy
|
gptkb:ristocetin_cofactor_activity_test
gptkb:von_Willebrand_factor_antigen_test
blood tests
|
|
gptkbp:firstDescribed
|
1926
|
|
gptkbp:frequency
|
1 in 100 to 1 in 1000 people
|
|
gptkbp:hasType
|
Type 1
Type 2
Type 3
|
|
gptkbp:ICD-10_code
|
gptkb:D68.0
|
|
gptkbp:inheritance
|
autosomal dominant
autosomal recessive
|
|
gptkbp:namedAfter
|
gptkb:Erik_Adolf_von_Willebrand
|
|
gptkbp:OMIM
|
193400
|
|
gptkbp:prevalence
|
most common inherited bleeding disorder
|
|
gptkbp:riskFactor
|
gptkb:genetic_disorder
family history
|
|
gptkbp:symptom
|
bleeding gums
easy bruising
prolonged bleeding
frequent nosebleeds
heavy menstrual bleeding
|
|
gptkbp:treatment
|
gptkb:desmopressin
gptkb:antifibrinolytic_drugs
gptkb:von_Willebrand_factor_concentrates
|
|
gptkbp:bfsParent
|
gptkb:D68.0
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Von Willebrand disease
|