Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:medical_condition
|
| gptkbp:affects |
red blood cell production
nervous system function |
| gptkbp:alsoKnownAs |
cobalamin deficiency
|
| gptkbp:cause |
gptkb:peripheral_neuropathy
psychiatric symptoms megaloblastic anemia subacute combined degeneration of the spinal cord |
| gptkbp:causedBy |
gastrointestinal surgery
pernicious anemia chronic alcoholism insufficient dietary intake of vitamin B12 malabsorption of vitamin B12 certain medications (e.g., metformin, proton pump inhibitors) |
| gptkbp:complication |
gptkb:depression
gptkb:anemia infertility cognitive impairment neurological damage irreversible nerve damage |
| gptkbp:diagnosedBy |
serum vitamin B12 level
complete blood count (CBC) homocysteine level methylmalonic acid test |
| gptkbp:ICD-10_code |
E53.8
|
| gptkbp:prevalence |
more common in older adults
more common in vegans and vegetarians more common in people with gastrointestinal disorders |
| gptkbp:prevention |
adequate dietary intake of vitamin B12
supplementation in at-risk groups |
| gptkbp:riskFactor |
autoimmune disorders
elderly age gastrointestinal disorders vegan diet |
| gptkbp:symptom |
memory loss
fatigue jaundice shortness of breath weakness pallor difficulty walking glossitis cognitive disturbances numbness and tingling in hands and feet |
| gptkbp:treatment |
dietary modification
intramuscular vitamin B12 injections oral vitamin B12 supplements |
| gptkbp:bfsParent |
gptkb:Proton_Pump_Inhibitor
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
Vitamin B12 deficiency
|