VIM-type metallo-beta-lactamase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:cofactor |
zinc
|
| gptkbp:detects |
PCR
phenotypic assays |
| gptkbp:enzymeClassification |
metallo-beta-lactamase
|
| gptkbp:firstDescribed |
1999
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Pseudomonas_aeruginosa gptkb:Klebsiella_pneumoniae Gram-negative bacteria |
| gptkbp:function |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:gene |
blaVIM
|
| https://www.w3.org/2000/01/rdf-schema#label |
VIM-type metallo-beta-lactamase
|
| gptkbp:inhibitedBy |
gptkb:EDTA
|
| gptkbp:notableVariant |
gptkb:VIM-1
gptkb:VIM-2 gptkb:VIM-4 |
| gptkbp:publicHealthConcern |
gptkb:antibiotic
|
| gptkbp:resistantTo |
carbapenem antibiotics
antibiotic inactivation |
| gptkbp:spreadTo |
horizontal gene transfer
|
| gptkbp:bfsParent |
gptkb:antimicrobial_resistance_gene_VIM
|
| gptkbp:bfsLayer |
8
|