|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:cellubrevin
CED-7
VAMP-3
|
|
gptkbp:alternativeName
|
gptkb:cellubrevin
|
|
gptkbp:associatedWith
|
membrane fusion
|
|
gptkbp:biologicalProcess
|
endocytosis
exocytosis
SNARE binding
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
cytoplasmic vesicle membrane
|
|
gptkbp:discoveredBy
|
1993
|
|
gptkbp:encodes
|
VAMP3 protein
|
|
gptkbp:Entrez_Gene_ID
|
6845
ENSG00000135334
GC01P171282
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
vesicle-associated membrane protein 3
|
|
gptkbp:function
|
SNARE complex formation
involved in vesicle trafficking
|
|
gptkbp:HGNC_ID
|
12647
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
VAMP3 gene
|
|
gptkbp:interactsWith
|
gptkb:VAMP2
gptkb:SNAP23
syntaxin 4
|
|
gptkbp:length
|
117 amino acids (protein product)
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
1q24.2
|
|
gptkbp:mutationAssociatedWith
|
may affect vesicle trafficking
|
|
gptkbp:OMIM
|
605018
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:pathway
|
vesicle-mediated transport
endocytosis pathway
exocytosis pathway
|
|
gptkbp:proteinFamily
|
transmembrane domain
SNARE domain
synaptobrevin family
|
|
gptkbp:regulates
|
regulated by phosphorylation
regulated by ubiquitination
|
|
gptkbp:significance
|
not directly associated with major diseases
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:subcellularLocation
|
gptkb:Golgi_apparatus
gptkb:plasma_membrane
endosome membrane
|
|
gptkbp:UniProtID
|
Q15836
|
|
gptkbp:bfsParent
|
gptkb:VAMP3
gptkb:synaptobrevin
|
|
gptkbp:bfsLayer
|
7
|