Ubiquitin-specific protease 1
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:USP1
gptkb:ubiquitin_carboxyl-terminal_hydrolase_1 |
| gptkbp:associatedWith |
gptkb:Fanconi_anemia
|
| gptkbp:EC_number |
3.4.19.12
|
| gptkbp:expressedIn |
various tissues
highly in testis |
| gptkbp:function |
deubiquitinating enzyme
removes ubiquitin from target proteins |
| gptkbp:gene |
gptkb:USP1
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ubiquitin-specific protease 1
|
| gptkbp:interactsWith |
WD repeat-containing protein 48 (WDR48/USP1-associated factor 1)
|
| gptkbp:involves |
DNA repair
Fanconi anemia pathway |
| gptkbp:locatedOnChromosome |
gptkb:1p31.1
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:molecularWeight |
88 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
2I3T
|
| gptkbp:postTranslationalModification |
phosphorylation
autocleavage |
| gptkbp:regulates |
monoubiquitination of FANCD2
monoubiquitination of PCNA |
| gptkbp:UniProtID |
gptkb:Q9Y4E8
|
| gptkbp:bfsParent |
gptkb:UBS1
|
| gptkbp:bfsLayer |
6
|