|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:aminoAcidLength
|
76
|
|
gptkbp:category
|
post-translational modifier
small regulatory protein
|
|
gptkbp:covalentlyAttachedTo
|
lysine residues of substrate proteins
|
|
gptkbp:discoveredBy
|
gptkb:Aaron_Ciechanover
gptkb:Avram_Hershko
gptkb:Gideon_Goldstein
|
|
gptkbp:discoveredIn
|
1975
|
|
gptkbp:encodedBy
|
RPS27A gene
UBA52 gene
UBB gene
UBC gene
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
gptkbp:function
|
signal transduction
DNA repair
cell cycle regulation
protein degradation
regulation of protein turnover
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ubiquitin
|
|
gptkbp:involvedIn
|
gptkb:ubiquitin-proteasome_pathway
immune response
autophagy
endocytosis
|
|
gptkbp:locatedOnChromosome
|
chromosome 12 (UBC)
chromosome 15 (RPS27A)
chromosome 17 (UBB)
chromosome 19 (UBA52)
|
|
gptkbp:molecularWeight
|
8.5 kDa
|
|
gptkbp:NobelPrizeYear
|
gptkb:Aaron_Ciechanover
gptkb:Avram_Hershko
gptkb:Irwin_Rose
gptkb:2004_Nobel_Prize_in_Chemistry
|
|
gptkbp:PDB
|
gptkb:1UBQ
|
|
gptkbp:polyubiquitinChainsLinkedBy
|
lysine 27
lysine 11
lysine 29
lysine 33
lysine 48
lysine 6
lysine 63
methionine 1
|
|
gptkbp:postTranslationalModification
|
ubiquitination
|
|
gptkbp:removes
|
deubiquitinating enzymes
|
|
gptkbp:structure
|
beta-grasp fold
|
|
gptkbp:symbol
|
gptkb:UBB
gptkb:UBC
gptkb:RPS27A
gptkb:UBA52
|
|
gptkbp:UniProtID
|
gptkb:P0CG47
|
|
gptkbp:bfsParent
|
gptkb:UB1
gptkb:R-HSA-5673003
gptkb:1UNQ
gptkb:1UWH
gptkb:RPS27A
|
|
gptkbp:bfsLayer
|
7
|