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gptkbp:instanceOf
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gptkb:protein_secretion_system
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gptkbp:alsoKnownAs
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T2SS
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gptkbp:component
|
gptkb:ATPase
gptkb:secretin
membrane proteins
cytoplasmic proteins
periplasmic proteins
pseudopilus
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gptkbp:composedOf
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multiple protein components
|
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gptkbp:encodedBy
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gene clusters
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gptkbp:example
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gptkb:Vibrio_cholerae
gptkb:Pseudomonas_aeruginosa
gptkb:Klebsiella_pneumoniae
|
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gptkbp:foundIn
|
Gram-negative bacteria
|
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gptkbp:function
|
secretion of proteins across the outer membrane
|
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gptkbp:importantFor
|
pathogenicity
|
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gptkbp:locale
|
spans inner and outer bacterial membranes
|
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gptkbp:mechanismOfAction
|
piston-like movement of pseudopilus
|
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gptkbp:powerSource
|
ATP hydrolysis
|
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gptkbp:relatedTo
|
Type IV pilus
|
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gptkbp:requires
|
Sec or Tat pathway for inner membrane translocation
|
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gptkbp:role
|
bacterial virulence
|
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gptkbp:secretes
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gptkb:cholera_toxin
gptkb:protease
enzymes
toxins
lipase
pullulanase
|
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gptkbp:studiedIn
|
microbiology
|
|
gptkbp:transportation
|
folded proteins
|
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gptkbp:bfsParent
|
gptkb:Pilotins
|
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gptkbp:bfsLayer
|
8
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|
https://www.w3.org/2000/01/rdf-schema#label
|
Type II secretion system
|