Type II secretion system

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf protein secretion system
gptkbp:alsoKnownAs T2SS
gptkbp:component gptkb:ATPase
gptkb:secretin
membrane proteins
cytoplasmic proteins
periplasmic proteins
pseudopilus
gptkbp:composedOf multiple protein components
gptkbp:encodedBy gene clusters
gptkbp:example gptkb:Vibrio_cholerae
gptkb:Pseudomonas_aeruginosa
gptkb:Klebsiella_pneumoniae
gptkbp:foundIn Gram-negative bacteria
gptkbp:function secretion of proteins across the outer membrane
https://www.w3.org/2000/01/rdf-schema#label Type II secretion system
gptkbp:importantFor pathogenicity
gptkbp:locale spans inner and outer bacterial membranes
gptkbp:mechanismOfAction piston-like movement of pseudopilus
gptkbp:powerSource ATP hydrolysis
gptkbp:relatedTo Type IV pilus
gptkbp:requires Sec or Tat pathway for inner membrane translocation
gptkbp:role bacterial virulence
gptkbp:secretes gptkb:cholera_toxin
gptkb:protease
enzymes
toxins
lipase
pullulanase
gptkbp:studiedIn microbiology
gptkbp:transportation folded proteins
gptkbp:bfsParent gptkb:Pilotins
gptkbp:bfsLayer 8