Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:collagen |
| gptkbp:associatedWith |
gptkb:Stickler_syndrome
gptkb:Kniest_dysplasia osteoarthritis |
| gptkbp:biosynthesisLocation |
chondrocytes
|
| gptkbp:degradedBy |
collagenase
|
| gptkbp:discoveredBy |
gptkb:Miller_and_Matukas
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:EC_number |
not applicable
|
| gptkbp:encodedBy |
gptkb:COL2A1_gene
|
| gptkbp:foundIn |
gptkb:nucleus_pulposus
gptkb:collagen vitreous humor |
| gptkbp:function |
forms fibrils
provides tensile strength to cartilage |
| gptkbp:molecularWeight |
~300 kDa
|
| gptkbp:OMIM |
120140
|
| gptkbp:postTranslationalModification |
glycosylation
hydroxylation |
| gptkbp:structure |
triple helix
|
| gptkbp:subunit |
three alpha-1(II) chains
|
| gptkbp:UniProtID |
gptkb:P02458
|
| gptkbp:usedIn |
biomaterials
cartilage repair research |
| https://www.w3.org/2000/01/rdf-schema#label |
Type II collagen
|